Antigenic Domain 1 Is Required for Oligomerization of Human Cytomegalovirus Glycoprotein B
نویسندگان
چکیده
منابع مشابه
Antigenic domain 1 is required for oligomerization of human cytomegalovirus glycoprotein B.
Human cytomegalovirus (HCMV) glycoprotein B (gB) is an abundant virion envelope protein that has been shown to be essential for the infectivity of HCMV. HCMV gB is also one of the most immunogenic virus-encoded proteins, and a significant fraction of virus neutralizing antibodies are directed at gB. A linear domain of gB designated AD-1 (antigenic domain 1) represents a dominant antibody bindin...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2005
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.79.7.4066-4079.2005